2021 Ford E-350

Routine

Owners filed 22 complaints about this vehicle with federal regulators, most often about the engine. It has been recalled 6 times.

What fails
ComponentReportsCrashesFiresInjuries
Engine11
000
Steering3
000
Unknown or Other2
000
Service Brakes2
100
Traction Control System1
000
Steering › Hydraulic Power Assist › Power Steering Fluid1
000
Service Brakes, Hydraulic › Power Assist1
000
Fuel System, Diesel1
000

6 safety recalls

Part 573 reports
Engine25V793000
Filed Nov 17, 20257,046 vehiclesFord Motor Company

Defect. Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles that received an incomplete software update under recall 20V795. The engine cover may become excessively hot.

Risk. Direct contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

Remedy. Dealers will update the powertrain calibration for heat management under elevated idle conditions, free of charge. Owner notification letters were mailed January 7, 2026. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 25SC7. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning December 22, 2025.

Service Brakes, Hydraulic › Foundation Components › Hoses, Lines/Piping, and Fittings24V097000
Filed Feb 9, 202416,543 vehiclesFord Motor Company

Defect. Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake hydroboost unit may result in a sudden loss of power steering fluid.

Risk. A sudden loss of power steering fluid can result in a loss of power steering and power brake assist, increasing the risk of a crash.

Remedy. Dealers will replace the power steering pressure line and the hydroboost jumper line, free of charge. Vehicles in this recall were previously recalled under 22V-089 and owners will need to have the new remedy completed even if their vehicle was remedied under the prior recall. Owner notification letters were mailed on June 21, 2024. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 24S07.

Service Brakes, Hydraulic › Foundation Components › Hoses, Lines/Piping, and Fittings22V089000
Filed Feb 16, 202244,219 vehiclesFord Motor Company

Defect. Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake Hydroboost unit may result in a sudden loss of power steering fluid.

Risk. A sudden loss of power steering fluid can result in a loss of power steering and power brake assist, increasing the risk of a crash.

Remedy. Dealers will inspect the connection between the power steering lines and the Hydroboost unit, and replace the power steering lines, as necessary, free of charge. Owner notification letters were mailed on March 18, 2022. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 22S08.

Engine20V795000
Filed Dec 17, 202029,344 vehiclesFord Motor Company

Defect. Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. The underside of the engine cover may have mispositioned insulation, allowing the cover to get excessively hot.

Risk. Direct and continuous contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

Remedy. Ford will notify owners, and dealers will inspect the engine cover for gaps between the rubber seal and the insulation. If gaps are present, the dealer will install engine cover insulation patches in the right hand and left hand inner lower corners of the engine cover. The dealer will also update the powertrain calibration for heat management under elevated idle conditions should a vehicle be equipped with SEIC or BCP, free of charge. The recall began February 15, 2021. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S73.

Electronic Stability Control (esc)20V175000
Filed Mar 23, 20202,871 vehiclesFord Motor Company

Defect. Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. A wire harness in the rear of the vehicle may contact the vehicle frame, resulting in damage to the circuits that support the fuel pump and the anti-lock braking system (ABS).

Risk. Damage to the fuel pump circuit in the wiring harness could result in an unexpected engine stall. Damage to the ABS wiring can lead to reduction of ABS functionality and a loss of roll stability control (RSC) functionality. These scenarios increase the risk of a crash.

Remedy. Ford will notify owners, and dealers will inspect the wire harness for damage. If no damage is found, dealers will apply anti-abrasion tape over the area and ensure clearance to surrounding components. If damage is found, dealers will splice in new wire and apply anti-abrasion tape over the area and ensure clearance to surrounding components. All services will be performed free of charge. The recall began May 18, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S13.

Power Train › Driveline › Differential Unit20V099000
Filed Feb 21, 2020319 vehiclesFord Motor Company

Defect. Ford Motor Company (Ford) is recalling certain 2020 F-550 and 2021 E-350 and E-450 vehicles. The rear axle differential fluid may be below the minimum level, possibly resulting in a failure of the rear axle assembly and driveshaft separation.

Risk. If the driveshaft separates, there may be a loss of drive, increasing the risk of crash. Additionally, if the parking brake is not applied, unintended vehicle movement can occur and increase the risk of injury or crash.

Remedy. Ford will notify owners, and dealers will inspect the rear axle differential fluid level and adjust it, or replace the rear axle as necessary, free of charge. The recall began March 19, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S09.

What owners reported

Newest filings
Engine
Filed Sep 13, 2026NC

Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, August 25, 2026: "FOUND ENGINE IS KNOCKING, WILL NEED TO REPLACE MOTOR." Ford quoted $16,000.82 for a long-block replacement. The engine is available for inspection. This is the second engine failure on this VIN. In March 2023 at 83,575 miles the engine was rebuilt with new Ford parts (camshaft, sixteen lifters, rocker arms, cylinder heads) after a camshaft and lifter failure. On the day the rebuild was completed the shop recorded "03/31/2023- NEW ENGINE FAILED. ENGINE STARTED KNOCKING AND HAD NOISE COMING FROM TOP END." and Ford replaced the complete engine under warranty in April 2023 (Ford claim CAS-42271539-G0F3ZF). That Ford replacement engine is the one that has now failed, after 69,185 miles. Ford's own repair order of August 25, 2026 lists Safety Recalls 20S73 and 24S07 for this VIN at $0.00, i.e. not performed, while the vehicle sat at the Ford dealership. Ford Customer Experience declined assistance on August 25, August 28 and September 9, 2026 and closed the case. The same 7.3L engine has failed on nine vehicles in this fleet; NHTSA already holds VOQ 11582566, 11582592, 11582598, 11582601, 115

Engine
Filed Sep 13, 2026NC

Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER." The Ford service advisor wrote the same day: "The engine also has a misfire that is unrelated to the transmission concern." Ford quoted $4,376.35 for the ignition components and wrote: "AFTER REPAIRING TRANSMISSION WILL NEED TO DIAGNOSE ALL OTHER CONCERNS WITH VEHICLE, CANNOT DIAG ANYTHING AT MOMENT DUE TO NOT BEING ABLE TO DRIVE VEHICLE." Ford has not completed the engine diagnosis; on July 27, 2026 it advised against a compression test and offered one at $920.00. This is the second engine failure on this VIN. In January 2024 at 103,177 miles, the same Ford dealership diagnosed "Found a misfire and low compression on cylinder 3, ordered engine and replaced the engine with new intake gaskets, exhaust manifold gaskets, torque converter nuts, found the reinforcement cracked and replaced it" and installed a Ford service engine, part LC3Z-6006-B (Invoice 551352C; I paid $10,000.00). That Ford replacement engine is the one now misfiring, after at least 63,580 miles. Note on mileage: Ford's RO 593079 records 103,778 miles; Ford's own January 2024 invoice recorded 103,177 and independent records show 166,757

Engine
Filed Jan 31, 2026NC

Fatal Camshaft and lifter failure requiring an engine replacement

Engine
Filed Nov 28, 2025MA

Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420

Engine
Filed Feb 17, 2025IN

This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

Engine
Filed Feb 17, 2025IN

This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

Engine
Filed Feb 17, 2025IN

This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

Steering
Filed Nov 5, 2024PA

See attached document for complaint.

Service Brakes
Filed Aug 18, 2024OR

After hitting a very rough patch of interstate, our steering became very difficult. The driver thought that maybe we had a low tire, so looked for a place to pull over. We crested a hill, and there was an exit with a truck stop. As we attempted to slow for the exit, the driver discovered we had no brakes or power steering. Driver used the brakes on the trailer we were towing to slow us and bring us to a stop. Checked the brake fluid reservoir. It was empty. Bought more, but as soon as the pedal was pushed, it was gone. We were towed to a repair shop, and they discovered the high pressure line on the Hydroboost brake system had separated. The repair shop was able to find a replacement from Ford Motor Co., and repaired our motorhome. We had this exact component inspected 2 years ago when Ford issued an inspection report. We passed. This incident happened 2500 miles from home. When we arrived home, there was a letter from Ford (24N03) stating they were extending the "warranty" period on the high pressure line.

Unknown or Other
Filed Aug 1, 2024NY

Safety recall

Service BrakesCrash
Filed Jun 25, 2024OR

On 6/2/23, brakes failed to work when applying heavy pressure, causing a rear end collision.

Engine
Filed Apr 12, 2024NC

See attached document for complaint,

Engine
Filed Apr 12, 2024NC

See attached document for complaint,

Engine
Filed Apr 12, 2024NC

See attached document for complaint,

Steering
Filed Jul 6, 202340,000 milesFL

The contact owns a 2021 Ford E-350. The stated while driving into the driveway, the vehicle made an abnormal popping sound. The vehicle lost power steering functionality, and the brake pedal became spongy. Additionally, the contact stated that there was a trail of fluid in the driveway. The contact stated that upon opening the hood, he noticed that the brake line had fractured, and brake fluid was leaking inside the engine compartment. There was no further information provided. The manufacturer was notified of the failure and referred the contact to a dealer; however, the dealer could not accommodate the vehicle. The dealer was contacted and diagnosed the vehicle at the contact's residence. The dealer determined that unknown hoses needed to be replaced and the failure was related to NHTSA Campaign Number: 22V089000 (Steering, Service Brakes, Hydraulic). The dealer and the manufacturer informed the contact that the vehicle could not be covered under the recall as the recall was previously marked as complete. The contact stated that the dealer had not completed the recall repair on the vehicle. The vehicle was not repaired. The failure mileage was approximately 40,000.

Fuel System, Diesel
Filed Jul 1, 202213,667 milesFL

The contact owns a 2021 Ford E-350. The contact stated that while driving at undisclosed speeds, the power steering and brakes became inoperable. There were no warning lights illuminated. The vehicle was towed to the local dealer where it was diagnosed with loosened brake line fittings and an unknown fluid leak. The vehicle was repaired. The contact stated the failure was related to NHTSA Campaign Number: 22V013000 (Fuel System, Diesel). The manufacturer was contacted but no additional assistance was provided. The failure mileage was approximately 13,667.

Service Brakes, Hydraulic › Power Assist
Filed Jun 30, 202210,800 milesOH

The contact owns a 2021 Ford E-350. The contact stated that the vehicle was included in NHTSA Campaign Number: 22V089000 (Steering, Service Brakes, Hydraulic) and the vehicle was inspected. During the inspection, there were no leaks found. The contact stated while driving approximately 65 MPH after the inspection, the vehicle lost power steering functionality. The contact coasted the vehicle off the highway. The contact stated that while driving afterward and attempting to depress the brake pedal, the vehicle failed to respond as designed. The contact pulled over and had the vehicle towed to the dealer where the recall repair was completed. The manufacturer was made aware of the failure. The approximate failure mileage was 10,800.

Steering
Filed Apr 1, 202222,000 milesNV

The contact owns a 2021 Ford E-350. The contact's wife was driving into a parking lot at approximately 5 MPH when the power steering and the brakes failed. The contact's wife was able to safely stop the vehicle. The contact stated that his wife had not observed any warning lights being illuminated. The contact's wife examined the vehicle and noticed that there was red fluid puddling on the ground and a hissing sound coming from the driver’s side under the engine. The vehicle had not been towed to a dealer and had not been diagnosed or repaired. The contact researched online and related the failure to NHTSA Campaign Number: 22V089000 (Steering, Service Brakes, Hydraulic). The manufacturer had not been informed of the failure. The failure mileage was approximately 22,000. Consumer purchased the unit in Las Vegas on March 13th with 21,477 miles on the odometer and it failed on April 1st, with 22,018 miles on the odometer.

Unknown or Other
Filed Aug 4, 2021MO

The vehicle was very difficult to keep on the road. It wanted to go all over the road. It was a struggle to keep it in the lane. We took the RV back to the dealer we bought it from & they told us they didn't work on that & to find a Ford dealer that would work on it. After many phone calls I found a Ford dealer that would work on it. They told us nothing was wrong with the steering. It was engineered badly. They said the back end was too heavy & was making the front end light & "squirrely" & difficult to steer. They said it needed heavier suspension on the back end. They suggested heavier springs or installing suspension air bags. The other problem was the dash board lights started flashing off & on. Most of the time the dashboard lights were off. We could only see the speedometer, gas gauge & other gauges when the lights flashed on. But we didn't know if they were accurate when they were on. At one point we smelled wires burning & then the cruise control went out. The electrical problems started 07/19/2021.

Steering › Hydraulic Power Assist › Power Steering Fluid
Filed Jul 13, 20215,000 milesAK

The contact owns a 2021 Ford E-350. The contact stated while driving 60 mph, the contact started to smell a burning odor coming from the RV. The contact attempted to pull over the RV to the side of the roadway however, the RV became difficult to steer. The contact pulled over the RV and checked underneath the RV and the front hood and noticed that power steering fluid had leaked all over the engine. The contact continued driving to his destination and then had the RV towed to an RV lot. The RV was not diagnosed nor repaired. The manufacturer was made aware of the failure. The failure mileage was approximate 5,000.

20 of 22 complaints, reproduced as filed.

Across model years

Worst on record: 1997
YearComplaintsRecallsFiresDeathsAssessment
20270100Routine
20260100Routine
20252100Routine
20242100Routine
20232200Routine
202214300Routine
2021 — this page22600Routine
20202000Routine
20193010Routine
20183400Routine
201713410Routine
20165300Routine
20157200Routine
2014171110Routine
201313900Routine
2012161210Routine
2011192000Routine
2010171800Routine
2009102720Routine
2008393200Routine
2007183510Routine
2006533920Routine
2005551620Routine
2004461111Fatalities reported
200346841Fatalities reported
200253510Routine
200152430Routine
200059832Fatalities reported
199972932Fatalities reported
199863810Routine
199779562Fatalities reported
199650310Routine
199569331Fatalities reported
199451550Routine
199343340Routine
199241340Routine
199119120Routine
199023210Routine

Compare every E-350 year →

Reading this record

No unusual pattern of severe incidents in the complaint record.

Complaint counts track how many cars were sold and how long they have been on the road as much as they track quality. A common model from 2013 has had a decade to accumulate reports; a rare one from last year has not. The signal worth weighing is in the severity columns, in whether the same component keeps appearing, and in whether the manufacturer eventually opened a recall for it.

Recall repairs are free for as long as the recall stands. Check whether a specific car still has open work at NHTSA's VIN lookup.

Most recent recall on file: Nov 17, 2025. Source: NHTSA Office of Defects Investigation.